Cold chain partnerships are largely a matter of trust. Once cargo is handed to a forwarder or carrier, shippers must rely on their partners to safely steward their temperature-sensitive products through the cold chain. Effective, reliable partners should show low levels of wasted product from supply chain errors, because a tested and refined process best controls temperature fluctuations. We enlisted insight from; Guy Hoskens, Clinical Supply Chain Logistics Expert, Janssen, Alan Kennedy, Founder, Team-up Global and Luiz Barberini, Operations Manager- External Manufacturing Latin America Head, Bayer to examine some key collaboration mistakes that could trigger a break in a cold chain.